Lung Tumor

Pathology

The term used for lung tumor derived from epithelial tumors airway
(Bronchus, bronchioles and alveoli). According to the WHO classification, 88% of primary lung cancers occur from 4 main cell epidermoid cells, small cell (oat cell), gland cell, large cell (large cell), and the remaining undifferentiated carcinoma, carcinoid, bronchial gland tumors (including adenoid cystic carcinoma and mucoepidermoid tumors), as well as other tumor types that are not specific.
Classification of primary lung tumors according to WHO.

1. Epidermoid cell carcinoma = Tues skuamus (squamous cell carcinoma), consists of:
a. High differentiation (well differentiated)
b. Differentiation medium (moderatly differentiated)
c. Low differentiation (poorly differentiated)

2. Small cell carcinoma (small cell carcinoma), consists of:
a. Oat cell carcinoma (oat cell carcinoma)
b. Intermadia cell type (intermediate cell type)
c. The combination of oat cell carcinoma (combined oat cell carcinoma)

3. Gland carcinoma (adeno carcinoma), consists of:
a. Asiner gland carcinoma
b. Gland carcinoma papillary
c. Carcinoma bronkiolo alveoler
d. Solid carcinoma with mucus formation (solid Ca with mucous formation)

4. Large cell carcinoma (large cell carcinoma)
a. Datia cell carcinoma (giant cell Ca)
b. Clear cell carcinoma (clear cell Ca)

5. Mucous gland carcinoma (adeno squamous carcinoma)

6. Carcinoid tumor (carcinoid tumor)

7. Mukoepidermoid carcinoma

8. Adenoid cystic carcinoma

9. Sarcoma and other soft tissue tumors

10. Other carcinoma not otherwise specified

Epidermoid cell carcinoma

Marked with the production of keratin, intercellular bridges, keratohialin granules and presence of neoplastic cell groups are clearly delimited and can be regarded as a typical illustration.

Small cell carcinoma

Small cell carcinoma or oat cell marked a very small cells that do not have differentiation at all. Generally, these cells are round or oval, sometimes spindle-shaped.

Gland carcinoma

Histological criteria include architectural gland and / or mucus production.

Large cell carcinoma

Provide an overview of neoplasms without the above characteristics.
Each cell has a different response to therapy, so that the correct histological diagnosis is a major step to proper treatment. In the past 25 years, with an unknown cause, replace adenocarcinoma cell carcinoma histological subtypes skuamus as most of all genders and ethnicities.

Selection of therapy is largely based on histological classification, whether including small cell carcinoma or not (non-small cell carcinoma). Small cell carcinoma, as they are found usually occur deployment, so that surgery is not an appropriate therapy, but chemotherapy as primary therapy with or without radiotherapy. In contrast, non-small cell carcinoma is a tumor that is localized, so it can be treated with surgery or with chemotherapy. However, non-small carcinoma of the response to chemotherapy response was not as good as small cell carcinoma.